The Founders
Albert Szent-Györgyi
ELECTRONIC PROPERTIES OF BIOLOGICAL MACROMOLECULES
- Biological macromolecules (proteins, DNA) are electron conductors.
- The movement of delocalized electrons through the conducting band of biological macromolecules causes its dynamics.
- Molecular dynamics is a basic prerequisite for communication between biological macromolecules
Herbert Fröhlich
SELECTIVE LONG-DISTANCE INTERACTION BETWEEN BIOLOGICAL MOLECULES
- The dynamics of a biological molecule is transferred to the water and propagates as a dipole oscillation long distance around the molecule.
- Attractive forces are generated between biological molecules oscillating with the same frequency (the resonant interaction).
- The resonant interaction allows highly specific and effective recognition and targeting between molecules in the biological space overcrowded with billons of molecules.
Hermann Emil Fischer
SPECIFIC CHEMICAL BINDING BETWEEN BIOLOGICAL MOLECULES
- The specific chemical binding between biological molecules is determined by their structural complementarity (the lock and key concept).